Hwayeon Ryu, associate professor of mathematics, along with 榴莲app官方网站入 students and an alumnus published a paper in Mathematical Biosciences and Engineering on investigating immune dysregulation in COVID-19.
榴莲app官方网站入 students Pagnapech 鈥淧ech鈥 Ngoun 鈥26 and Nicolas Alvarez 鈥27, alumnus Ayesh Awad 鈥24, and Associate Professor of Mathematics Hwayeon Ryu published a peer-reviewed article titled聽鈥溾澛爄n Mathematical Biosciences and Engineering, one of the leading journals in the field of mathematical biology.
This article investigates how the human immune system responds to SARS-CoV-2 infection, with a particular focus on natural killer cells and cytokine regulation and their roles in determining disease severity. Using a mathematical, within-host model that combines viral dynamics with immune interactions, the study explores how different immune responses can lead to either viral clearance or severe inflammation. The findings provide insight into key immune mechanisms and offer guidance for identifying potential targets for future COVID-19 treatments. This work is a result of聽a聽National Science Foundation-funded project听辞苍听COVID-19 mathematical modeling.
is an interdisciplinary journal promoting cutting-edge research, technology transfer and knowledge translation about complex data and information processing at the interface of mathematics, biology, medicine and engineering.